US President Barack Obama has hailed the death of al-Qaeda leader Osama Bin Laden as a "good day for America," saying the world is now a safer and a better place.
Bin Laden was killed in a raid by US special forces on a compound in the Pakistani city of Abbottabad.
He is believed to have ordered the attacks on New York and Washington on 11 September 2001, as well as a number of other deadly bombings.
He topped the US "most wanted" list.
But his details on the list have now been updated with a simple banner indicating his current status: "Deceased".
DNA tests carried out after the operation indicated with "99.9%" certainty that the man shot dead was Osama Bin Laden, US officials said.
He was buried at sea after a Muslim funeral on board an aircraft carrier in the north Arabian Sea, Pentagon officials said.
President Obama has praised the "heroes" who carried out the operations and in a speech to congressional leaders, called for them to show "the same sense of unity that prevailed on 9/11".
The US has put its embassies around the world on alert, warning Americans of the possibility of al-Qaeda reprisal attacks for Bin Laden's killing.
CIA director Leon Panetta said al-Qaeda would "almost certainly" try to avenge the death of Bin Laden.
The US president's chief counter-terrorism advisor, John Brennan, said that though weakened, al-Qaeda, remained a danger.
"It may be a mortally wounded tiger but it still has some life in it," he said.